Genetics Problem Spaces

 

Introduction

 

Problem Spaces

Behavioral Genetics

Overview

Intro Exercise
Research Questions
Literature
Resources

 

Assignments

 

Student Projects

Behavioral Genetics

Research Tools

 

Web Resources

 

Caenorhabditis Genetics Center

Caenorhabditis elegans WWW Server

 

Wormbase

 

C. elegans online

 

RNAi Vectors

 

Reverse Genetics Techniques

 

Wisconsin Worm Project

 

 

 

On-Line Manuals

 

Hubbard Manual Part I

 

Hubbard Manual Part II

 

Worm Started Manual

 

 

Worm Strains currently available at BSC

 

Strain

Genotype

Description

N2

 

Wild Isolate Bristol England – standard lab strain

CB1033

che-2

Defective in ion chemotaxis

PR674

che-1

Defection in ion chemotaxis to all attractants except pyridine and tryptophan

MT5300

odr-4

Defective in chemotaxis to some volatile odorants including benzaldehyde, diacetyl, 2,4,5-trimethyl thiazole. Temperature sensitive

CX2304

odr-2

Defective in chemotaxis to some volatile odorants including benzaldehyde, isoamyl alcohol.

CX2065

odr-1

Defective in chemotaxis to some volatile odorants including benzaldehyde, 2-butanone, isoamyl alcohol.

UT1

lrn-1

Associative learning deficient in several assays.  Non-associative learning normal.

UT2

lrn-2

Associative learning deficient in several assays.  Non-associative learning normal.

 

RNAi vectors available

 

him-14 RNAi vector – generate 5-7% males at the end of brood

 

hsp110 RNAi vector- knock down expression of hsp110 gene.