Links to Important Websites

Working Group on Civilian Biodefense (how to handle a biological attack!) you have to go through a few links but eventually can learn about anthrax, tularemia, smallpox, botulism toxin and plague.

http://www.ama-assn.org/ama/pub/category/6232.html

Victorian Government links with background and information on most common bioterrorist weapons.

http://www.dhs.vic.gov.au/phd/bioterrorism/

Mad Cow disease and TSEs

US Food and Drug Administration info about mad cow disease

http://www.fda.gov/oc/opacom/hottopics/bse.html

All about Prions

http://www.microbe.org/news/prions.asp

BBC news report on CJD

http://news.bbc.co.uk/1/hi/special_report/1999/06/99/bse_inquiry/360343.stm

Laughing death in New Guinea

http://whyfiles.org/012mad_cow/6.html

Mad cow- CJD – a variety of links of all kinds

http://www.rense.com/health/madcowdata.html

The official mad cow disease page

http://www.mad-cow.org/

a general one-pager on prion proteins

http://science-education.nih.gov/nihHTML/ose/snapshots/multimedia/ritn/prions/prions1.html

Keeping mad cow disease out of the US

http://www.fda.gov/fdac/features/2001/201_cow.html

Chronic wasting disease in NY

http://www.dec.state.ny.us/website/dfwmr/wildlife/deer/cwd.html

http://msnbc.msn.com/id/7349409/

http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WSN-418PWX6-4&_coverDate=05%2F16%2F1997&_alid=266556599&_rdoc=1&_fmt=&_orig=search&_qd=1&_cdi=7051&_sort=d&view=c&_acct=C000037418&_version=1&_urlVersion=0&_userid=681889&md5=e0090a215b8f5fd4b38ecc43e6bad916

http://www.cell.com/content/article/abstract?uid=PIIS0092867400802329

Good website with structure and prion protein links

http://www.cmpharm.ucsf.edu/~wallacea/nobel.html

Prion diseasese

http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/P/Prions.html

Alzheimer’s disease

Alzheimer’s association

http://www.alz.org/

Alzheimer’s disease education and referral center – film on Alzheimer’s progression

http://www.alzheimers.org/

Alheimer’s disease international

http://www.alz.co.uk/

NIH Medline plus Alzheimer’s page – Overviews – What is Alzheimer Disease (Dolan Learning Center) is the one I used in class

http://www.nlm.nih.gov/medlineplus/alzheimersdisease.html

Transcription/Translation/Gene expression

Genetic Code

http://psyche.uthct.edu/shaun/SBlack/geneticd.html

Transcription and translation (same one as replication)

http://www.johnkyrk.com/DNAtranscription.html

Really cool website showing transcription and translation in 3-D – from my alma mater!

http://vcell.ndsu.nodak.edu/animations/

Cancer Links

p53 tumor suppressor protein

http://www.ncbi.nlm.nih.gov/books/bv.fcgi?call=bv.View..ShowSection&rid=gnd.section.107

http://www.infobiogen.fr/services/chromcancer/Genes/P53ID88.html

American Cancer Society

http://www.cancer.org/docroot/home/index.asp

Cancer figures 2004 – Adobe file with tons of information

Cancer Cell Cam – human melanoma cells growing in culture real-time….

http://www.cellsalive.com/cam1.htm

National Cancer Institute (NCI) of the National Institutes of Health (NIH) – lots of information on cancers and clinical trials

http://www.cancer.gov/

Breast cancer information http://imaginis.com/breasthealth/genetic_risks.asp , http://www.nlm.nih.gov/medlineplus/breastcancer.html , http://condor.bcm.tmc.edu/ermb/bcgd/bcgd.html , http://www.ncbi.nlm.nih.gov/disease/Breast-ovary.html

Genetic Disease Case study information

Cystic Fibrosis information http://www.cff.org/home/ , http://www.cysticfibrosis.com/ , http://www.nlm.nih.gov/medlineplus/cysticfibrosis.html , http://www.ccff.ca/

Muscular dystrophy information http://www.mdausa.org/ , http://www.parentprojectmd.org/news/latest/index.html , http://www.ncbi.nlm.nih.gov/disease/DMD.html http://www.nlm.nih.gov/medlineplus/musculardystrophy.html

Huntington’s Disease information http://www.hdsa.org/ , http://www.ninds.nih.gov/disorders/huntington/huntington.htm , http://www.hda.org.uk/ , http://www.nlm.nih.gov/medlineplus/huntingtonsdisease.html

Inheritance and Mendelian Genetics

Mendel’s experiments in animation and described (good for review of what we did in class!)

http://www.mendel-museum.org/eng/1online/experiment.htm

Mendelian Genetics: Principles of Segregation

http://www.accessexcellence.org/RC/VL/GG/mendel.html - simple explanation and diagrams

http://staff.jccc.net/pdecell/transgenetics/monohybrid1.html

Mendelian Genetics: Principle of Independent Assortment

http://staff.jccc.net/pdecell/transgenetics/independent.html

Recessive and Dominance inheritance

http://www.accessexcellence.org/RC/VL/GG/recessive.html

X-linked inheritance

http://www.accessexcellence.org/RC/VL/GG/x-linked.html - hemophilia example

Human single-gene disorders

http://www.wellcome.ac.uk/en/genome/genesandbody/hg06b006.html

DNA structure

Animated tutorial on DNA structure – requires Chime though, which I don’t have!

http://molvis.sdsc.edu/dna/index.htm

Great animation and description of DNA, replication, transcription, translation – this is the one I used in class

http://www.johnkyrk.com/DNAanatomy.html

Very straight-forward tutorial on DNA structure

http://www.rothamsted.bbsrc.ac.uk/notebook/courses/guide/dnast.htm#Com

DOE (Department of Energy) genome page – include the page for the human genome project

http://www.doegenomes.org/

Human Genome Project Primer – may be useful for answering some questions!

Powerpoint format Adobe acrobat (.pdf) format

Howard Hughes Medical Institute Blazing a Genetic Trail – great site about finding the cystic fibrosis gene and other information!

http://www.hhmi.org/genetictrail/

National Center for Biotechnology Information (NCBI) site – contains links for Online Mendelian Inheritance in Man (OMIM – see pgs 25-26 in your book), map viewer and other good sites!

http://www.ncbi.nlm.nih.gov/projects/genome/guide/human/

The NCBI Genes and Disease site (see pg 26 in your book) – more student friendly way to find diseases that have been mapped to chromosomes

http://www.ncbi.nlm.nih.gov/books/bv.fcgi?call=bv.View..ShowSection&rid=gnd.preface.91

Human Gene Map at the National Center for Biotechnology Information (NCBI) site – updated regularly

http://www.ncbi.nlm.nih.gov/projects/genome/genemap99/

Weizmann Institute of Science – gene cards – another place you can look up a gene

http://bioinfo.weizmann.ac.il/cards/index.shtml

Stem Cells:

National Institutes of Health Stem Cell Research and Information – Federal government information on stem cells.

http://stemcells.nih.gov/info/basics/StemCellBasics.pdf

http://www.ninds.nih.gov/funding/research/stem_cell/

http://stemcells.nih.gov/info/scireport/ pdf report on stem cells

National Reference Center for Bioethics Literature – huge sources of literature in all aspects of bioethics

http://www.georgetown.edu/research/nrcbl/

Science News Presented by BIO: Biotechnology Industry Organization

Information about MANY topics that we cover in this course.

http://science.bio.org/

Stem Cell Research News – independent organization that reports on stem cell research.

http://www.stemcellresearchnews.com/

Your Genes, Your Choices: Exploring the Issues Raised by Genetic Research – Department of Energy site on a variety of ethical issues.

http://www.ornl.gov/sci/techresources/Human_Genome/publicat/genechoice/index.html

Genetics Science Learning Center – fun animation of stem cells

http://gslc.genetics.utah.edu/units/stemcells/

Gene therapy – SCID example

http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/G/GeneTherapy.html

Molecular Medicine in Action website – pretty advanced animations of various processes – including using viruses in gene therapy

http://www.iupui.edu/%7Ewellsctr/MMIA/htm/animations.htm

Clinical trials of all kinds of research – type in ‘stem cells’ and you will see a bunch of trials!

http://www.clinicaltrials.gov/

Stem Cell lines available for Federally funded research

http://stemcells.nih.gov/research/registry/eligibilityCriteria.asp

Cloning:

Human Genome Project cloning fact sheet

http://www.ornl.gov/sci/techresources/Human_Genome/elsi/cloning.shtml

A pro human cloning website – pretty interesting

http://www.humancloning.org/

Another human cloning website that is not as biased!

http://www.globalchange.com/clonlink.htm

Just like stem cell guy – this is has a lot of cloning facts and a cloning cartoon

http://gslc.genetics.utah.edu/units/cloning/

Therapeutic Cloning – information from the American Federation for Aging Research (also has some good links to other information)

http://www.infoaging.org/b-cloning-3-therapeutic.html

Scientific American article on how therapeutic cloning is done – nice pictures

http://www.sciam.com/article.cfm?articleID=00016CF7-CE54-1CF4-93F6809EC5880000